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Performance & Recovery

B12 Methylcobalamin

The active form of B12. Most injections and supplements use cyanocobalamin, which your body has to convert first.

Pricing in reviewMember and subscription pricing at launch
In the box
  • Compounded vial, 30 day supply
  • Insulin syringes, 30
  • Alcohol swabs
  • Sharps container
  • Dosing card and video
  • Clinician chat, ongoing
Add to cart and check out, a licensed clinician reviews your order before anything ships. Fully refunded if not approved.
Two minutes, no appointment. A licensed clinician reviews your answers and your order before anything ships.
B12 Methylcobalamin
Reviewed by people you can meetA clinical team that sees you in person, not only on a form.
Dr. Krystle Etri
Dr. Krystle EtriNaturopathic Doctor, West Hollywood. Reviews your order and builds your plan.
Lara Cemaletin
Lara CemaletinRegistered Nurse, BSN, New York. Peptide consultations and your first injection, at the club.

Every order is cleared by a licensed clinician before the pharmacy fills it. Labs can be drawn at any club. Meet the whole team →

Build the protocol

B12 Methylcobalamin works better with three things.

B12 works inside the methylation cycle. It needs its partners to do the job.

Active folate and B6 are the other half of the cycle B12 runs; without them B12 stalls.
$28
B vitamins protect the brain best when omega-3 status is adequate. EPA and DHA complete the pair.
$46
Magnesium is the cofactor for the energy enzymes B12 supports, and for restful sleep.
$26
Chosen by our clinical team for this peptide. Your clinician reviews the whole order together. Member pricing applies at checkout.

The form matters more than most people realise

B12 is required to make red blood cells, to maintain the myelin around nerves, and to run the methylation reactions cells depend on. Low status is common and under recognised, particularly in people who eat little animal protein, anyone over fifty, and anyone on long term acid reducing medication or metformin.

The form matters more than most people realise. Methylcobalamin is the form your body uses directly. Cyanocobalamin, which is what most injections and supplements contain because it is cheaper and more stable, has to be converted first, and it carries a cyanide group your body then has to clear. That is the one honest differentiator on this product.

What it supports
  • Methylcobalamin is one of the two coenzyme forms the body uses directly, with no conversion step
  • Injected rather than swallowed, which makes absorption through the gut irrelevant
  • Donates a methyl group in the reaction that converts homocysteine to methionine
  • If your B12 is already adequate you will not feel much, which is how vitamins work and worth knowing before you buy
How it works
It is already active.

Methylcobalamin is one of two coenzyme forms your body actually uses. No conversion step is required.

Injection bypasses absorption problems.

B12 absorption depends on intrinsic factor and a healthy stomach and ileum. Injection makes that irrelevant, which is why people with absorption issues are prescribed injections rather than tablets.

It feeds the methylation cycle.

Methylcobalamin donates a methyl group in the reaction that converts homocysteine to methionine, which sits upstream of a lot of cellular work.

The mechanism

It is already active.

The protocol

Intramuscular or subcutaneous injection, typically weekly. The 10 mL vial is a long supply at that frequency. Store refrigerated and protected from light. The solution is deep red, which is the vitamin itself.

As directed by your clinician.
Pairs well with
  • Vitamin IVs, which cover the same ground from the club side
  • Infrared Sauna or Ice Baths, for anyone whose reason for being here is energy
  • Lymphatic Massage, as general background support
Who it is not for

B12 is water soluble and has a wide safety margin, but this is still a prescription product. Not in pregnancy or breastfeeding without clinician sign off. Anyone with Leber's hereditary optic neuropathy should avoid it. If you have a cobalt allergy, say so.

Questions
Why methylcobalamin over cyanocobalamin?
It is the active form, so your body skips a conversion step and does not have to clear a cyanide group. It costs more and it is the better product.
Will it give me energy?
If your B12 is low, noticeably. If it is already adequate, you will not feel much. That is how vitamins work.
Can I take too much?
It is water soluble and the excess is excreted. The margin is wide, which does not mean dose is irrelevant.
Why does my urine turn bright?
Excess B vitamins are excreted. It is harmless and expected.
How often?
Weekly is typical. Your clinician sets it against your levels.
Should I test first?
If you want to know whether you need it, yes. Serum B12 plus methylmalonic acid gives the honest picture. Our in club doctors will run it.
Why is it part of a protocol rather than sold on its own?
Same answer as Lipo-Mino. It supports a protocol rather than being one.
In practice

Injection bypasses absorption problems.

Book a Consultation

A clearance is not a consultation.

Every order here is reviewed by a licensed clinician before anything ships. That is a clearance, and it is included. A consultation is a different thing. It happens in person at the club, with a Remedy Place doctor who can order blood work, review your history and build a protocol around the therapies in the room, including the things we do not ship.

Book a Consultation →

Clinical services are provided by licensed clinicians. Therapies are prescribed or recommended following a clinical evaluation, where appropriate.

These compounded medications have not been approved by the FDA. The FDA has not evaluated statements regarding the benefits of these therapies. These products are not intended to diagnose, treat, cure or prevent any disease. Individual results vary. Compounded medications carry known and unknown risks that should be discussed with your clinician.